Table 7.

Efficacy analyses with binary definitions of adherence (for sensitivity)

Outcome	Efficacy with binary definition of adherence (full vs not full)	Efficacy with binary definition of adherence (at least five day course vs less than five day course)	Efficacy with binary definition of adherence (at least one tablet vs no tablets)
Adjusted between-group mean difference in symptom severity between days 2 and 4 postrandomisation	−0.10 (−0.20 to 0.01)	−0.08 (−0.18 to 0.01)	−0.07 (−0.15 to 0.01)
OR for developing new or worsening symptoms in the 4 weeks postrandomisation	0.78 (0.62 to 0.98)	0.80 (0.65 to 0.98)	0.82 (0.69 to 0.98)
OR for reporting non-respiratory symptoms/side effects in the 4 weeks postrandomisation	1.43 (1.15 to 1.79)	1.35 (1.26 to 1.62)	1.29 (1.11 to 1.50)