Table IV.
Cox proportional hazard analyses of smoking-related factors.
| Positive expression | ||||
|---|---|---|---|---|
| Factors | LVD | Presence of iLV | COX-2 | MMP-9 |
| For urinary tract recurrence | ||||
| Hazard ratio | 1.02 | 2.5 | 2.1 | 2.0 |
| 95% CI | 0.99-1.05 | 1.3-4.8 | 1.1-3.9 | 1.1-3.6 |
| P-value | 0.087 | 0.007 | 0.018 | 0.026 |
| For subsequent metastasis | ||||
| Hazard ratio | 1.05 | 5.6 | 8.3 | 3.5 |
| 95% CI | 1.01-1.1 | 2.5-12.3 | 2.5-27.9 | 1.5-8.4 |
| P-value | 0.002 | <0.001 | <0.001 | 0.005 |
LVD, lymphatic vessel density; iLV, intratumoral lymphatic vessel s; COX, cyclooxygenase; MMP, matrix metalloproteinase; CI, confidence interval.