Table 1a.
Up-regulated proteins identified and quantified by 2D-LC-MALDI-TOF/TOF.
| ID | Name | Mice at 6 weeks | Mice at 12 weeks | ||
|---|---|---|---|---|---|
| APOE −/− vs WT | a EF | APOE −/− vs WT | a EF | ||
| Q60590 | Alpha-1-acid glycoprotein 1 precursor | c1.7 | 1.2 | ||
| P07361 | Alpha-1-acid glycoprotein 2 precursor | e2.1 | 1.5 | ||
| Q00898 | Alpha-1-antitrypsin 1–5 precursor | c2.6 | 1.4 | ||
| P29699 | b Alpha-2-HS-glycoprotein precursor | c1.3 | 1.2 | e1.3 | 1.2 |
| Q61838 | Alpha-2-macroglobulin precursor | c1.4 | 1.1 | ||
| P06728 | b Apolipoprotein A-IV precursor | c1.9 | 1.1 | c1.7 | 1.1 |
| P34928 | Apolipoprotein C-I precursor | c2.2 | 1.6 | ||
| Q01339 | b Beta-2-glycoprotein 1 precursor | e1.3 | 1.3 | e1.5 | 1.4 |
| Q61147 | Ceruloplasmin precursor | c1.4 | 1.2 | ||
| P16294 | Coagulation factor IX precursor | e1.4 | 1.3 | ||
| O88947 | Coagulation factor X precursor | e1.3 | 1.3 | ||
| Q02105 | Complement C1q subcomponent subunit C precursor | e1.5 | 1.5 | ||
| P06684 | Complement C5 precursor | e1.2 | 1.1 | ||
| Q8K182 | Complement component C8 alpha chain precursor | d1.7 | 1.4 | ||
| Q8BH35 | Complement component C8 beta chain precursor | e1.3 | 1.3 | ||
| Q8VCG4 | Complement component C8 gamma chain precursor | d1.5 | 1.3 | ||
| P03953 | Complement factor D precursor | e2.0 | 1.8 | ||
| Q06770 | Corticosteroid-binding globulin precursor | d1.7 | 1.4 | ||
| Q9ERU9 | E3 SUMO-protein ligase RanBP2 | e1.4 | 1.3 | ||
| Q01279 | Epidermal growth factor receptor precursor | c1.5 | 1.1 | ||
| Q8K0E8 | b Fibrinogen beta chain precursor | c1.3 | 1.1 | c1.6 | 1.1 |
| Q8VCM7 | b Fibrinogen gamma chain precursor | c1.3 | 1.1 | c1.8 | 1.1 |
| Q08879 | Fibulin-1 precursor | e1.8 | 1.6 | ||
| P13020 | Gelsolin precursor | e1.2 | 1.2 | ||
| Q61646 | Haptoglobin precursor | c3.3 | 1.3 | ||
| Q91X72 | b Hemopexin precursor | c1.3 | 1.1 | c1.5 | 1.1 |
| P01873 | Ig mu chain C region membrane-bound form | c3.5 | 1.5 | ||
| P08071 | Lactotransferrin precursor | d2.2 | 1.3 | ||
| P51885 | Lumican precursor | e1.3 | 1.2 | ||
| P11588 | Major urinary protein 1 precursor | c2.0 | 1.4 | ||
| P41317 | Mannose-binding protein C precursor | e1.2 | 1.1 | ||
| Q6KCD5 | Nipped-B-like protein | e2.7 | 1.4 | ||
| P11680 | Properdin precursor | e1.5 | 1.4 | ||
| P19221 | b Prothrombin precursor | c1.4 | 1.1 | c1.3 | 1.1 |
| Q9JJT9 | RNA U small nuclear RNA export adapter protein | e1.6 | 1.6 | ||
| P70274 | Selenoprotein P precursor | e1.8 | 1.8 | ||
| Q91WP6 | Serine protease inhibitor A3N precursor | c1.6 | 1.2 | ||
| Q921I1 | Serotransferrin precursor | d2.7 | 1.9 | ||
| P12246 | Serum amyloid P-component precursor | c2.8 | 1.4 | ||
| Q9Z1T2 | Thrombospondin-4 precursor | e2.3 | 1.6 | ||
a
The error factor (EF) is an asymmetrical confidence interval, so the true ratio for the protein is expected to be found between the listed ratio multiplied by the EF and the listed ratio divided by the EF at 95% of the time.
b
Proteins are up-regulated at both time points.
c
Probability (p) value is less than 0.001.
d
Probability (p) value is greater than 0.001 but less than 0.01.
e
Probability (p) value is greater than 0.01 but less than 0.05.