Table 1.
Proteins identified that correspond to RD regions (regions of difference), which are genes absent in the M. bovis BCG genome but present in the M. tuberculosis H37Rv.
| Protein ID | Locus | Gene Name |
Description/Function | Regions of deletion (RD) | Filter1: ≥ 2 peptides in 4 of 6 runs for BCG |
Filter1: ≥ 2 peptides in 4 of 6 runs for Rv |
Total number of BCG peptides in all runs |
Total number of Rv peptides in all runs |
|---|---|---|---|---|---|---|---|---|
| NP_215143.1 | Rv3871 | hypothetical protein | 1RD | 0 | 6 | 0 | 66 | |
| NP_218391.1 | Rv3874 | esxB | protein EsxB | 1RD | 0 | 0 | 0 | 2 |
| NP_216214.1 | Rv3876 | hypothetical protein | 1RD | 0 | 6 | 0 | 14 | |
| NP_216388.1 | Rv3877 | transmembrane protein | 1RD | 0 | 6 | 0 | 94 | |
| NP_214806.1 | Rv1978 | hypothetical protein | 2RD/7RD | 0 | 6 | 0 | 82 | |
| NP_217821.1 | Rv1987 | chitinase | 2RD | 0 | 0 | 0 | 5 | |
| NP_216094.1 | Rv1578c | phiRv1 phage protein | 3RD | 0 | 0 | 0 | 8 | |
| NP_216099.1 | Rv1583c | phiRv1 phage protein | 3RD | 0 | 4 | 0 | 10 | |
| NP_215204.1 | Rv1586c | phiRv1 integrase | 3RD | 0 | 3 | 0 | 1 | |
| NP_216806.1 | Rv1508c | hypothetical protein | 4RD | 0 | 6 | 0 | 20 | |
| NP_216329.1 | Rv1509 | hypothetical protein | 4RD | 0 | 6 | 0 | 26 | |
| YP_177770.1 | Rv1513 | hypothetical protein | 4RD | 0 | 6 | 0 | 23 | |
| NP_215777.1 | Rv1516c | sugar transferase | 4RD | 0 | 6 | 0 | 18 | |
| NP_217894.1 | Rv1514c | hypothetical protein | 4RD | 0 | 4 | 0 | 26 | |
| NP_216031.1 | Rv1515c | hypothetical protein | 4RD | 0 | 2 | 0 | 1 | |
| NP_216028.1 | Rv1512 | epiA | nucleotide-sugar epimerase epiA | 4RD | 0 | 0 | 0 | 4 |
| NP_216863.1 | Rv2347c | esxP | ESAT-6 like protein | 5RD | 0 | 0 | 0 | 1 |
| NP_216865.1 | Rv2349c | plcC | phospholipase C 3 | 5RD | 0 | 0 | 0 | 2 |
| NP_216866.1 | Rv2350c | plcB | membrane-associated phospholipase C | 5RD | 0 | 1 | 0 | 1 |
| NP_216867.1 | Rv2351c | plcA | membrane-associated phospholipase C | 5RD | 0 | 0 | 0 | 1 |
| NP_216588.1 | Rv2072c | cobL | precorrin-6y methyltransferase CobL | 9RD | 0 | 0 | 0 | 3 |
| NP_218371.1 | Rv2073c | short-chain dehydrogenase | 9RD | 0 | 5 | 0 | 23 | |
| NP_216350.1 | Rv2074 | hypothetical protein | 9RD | 0 | 6 | 0 | 31 | |
| NP_216388.1 | Rv1977 | hypothetical protein | 7RD | 0 | 6 | 0 | 37 | |
| NP_218134.1 | Rv3617 | ephA | epoxide hydrolase | 8RD | 0 | 0 | 0 | 1 |
| NP_214798.1 | Rv3623 | lpqG | lipoprotein LpqG | 8RD | 0 | 5 | 0 | 28 |
| NP_214735.1 | Rv0221 | hypothetical protein | 10RD | 0 | 6 | 0 | 64 | |
| NP_214736.1 | Rv0222 | echA1 | enoyl-CoA hydratase | 10RD | 0 | 0 | 0 | 1 |
| NP_217174.1 | Rv2658c | prophage protein | 11RD | 0 | 2 | 0 | 6 | |
| NP_217175.1 | Rv2659c | phiRv2 prophage integrase | 11RD | 0 | 1 | 0 | 4 | |
| NP_216645.1 | Rv3120 | hypothetical protein | 12RD | 0 | 5 | 0 | 12 | |
| NP_215771.1 | Rv1255c | transcriptional regulatory protein | 13RD | 0 | 0 | 0 | 1 | |
| NP_215772.1 | Rv1256c | cyp130 | cytochrome P450 130 CYP130 | 13RD | 0 | 0 | 0 | 2 |
| YP_177976.1 | Rv1769 | hypothetical protein | 14RD | 0 | 6 | 0 | 31 | |
| NP_215612.1 | Rv1770 | hypothetical protein | 14RD | 0 | 6 | 0 | 129 | |
| NP_218405.1 | Rv1771 | oxidoreductase | 14RD | 0 | 6 | 0 | 68 |