Table 1.

Acute Doxorubicin-induced Cardiomyopathy Mouse Model

	Control	Dox	Dox + VIS
HR, beats/min	710±15	605±23**	640±17*
LVIDd, mm	3.22±0.05	3.19±0.09	3.08±0.06
LVIDs, mm	1.48±0.04	1.78±0.10*	1.51±0.04‡
FS, %	54±1	44±2***	51±1‡‡
Strain Rate, 1/s	23±1	16±1***	20±1*‡‡
N	8	7	8

Values are presented as mean ± SEM;

^*P<0.05

^**P<0.01

^***P<0.001 vs. Control;

^‡P<0.05,

^‡‡P<0.01, vs. Dox.