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. Author manuscript; available in PMC: 2015 Jun 10.
Published in final edited form as: Sci Transl Med. 2014 Dec 10;6(266):266ra170. doi: 10.1126/scitranslmed.3010189

Table 2.

Chronic Doxorubicin-induced Cardiomyopathy Mouse Model

Control Dox Dox+Vis
HR, beats/min 752±14 678±14** 707±21
LVIDd, mm 3.26±0.1 3.33±0.04 3.42±0.08
LVIDs, mm 1.54±0.07 1.91±0.1* 1.76±0.09
FS, % 53±1 43±2** 49±2
Strain Rate, 1/s 22±1 16±1** 20±2
N 4 8 7

Values are presented as mean ± SEM;

*

P<0.05

**

P<0.01

***

P<0.001 vs. Control;

P<0.05,

‡‡

P<0.01, vs. Dox.