Table 2.
Adverse Events possibly related to study drug
| Adverse Event | 1 | 2 | 3 | 4 | Total |
|---|---|---|---|---|---|
| Leukopenia | 8 | 1 | 0 | 0 | 19 |
| Thrombocytopenia | 2 | 0 | 0 | 0 | 19 |
| Neutropenia | 9 | 1 | 0 | 0 | 19 |
| Anemia | 4 | 1 | 2 | 1 | 19 |
| Other Investigations: (LFTs elevation, creatinine) | 4 | 5 | 1 | 0 | 19 |
| Cardiac | 1 | 0 | 0 | 0 | 19 |
| Gastrointestinal | 11 | 3 | 1 | 1 | 19 |
| General (constitutional) | 9 | 3 | 1 | 0 | 19 |
| Metabolism/nutrition | 3 | 2 | 3 | 1 | 19 |
| Musculoskeletal/connective tissue | 3 | 0 | 0 | 0 | 19 |
| Nervous system | 4 | 1 | 2 | 0 | 19 |
| Psychiatric | 1 | 0 | 0 | 0 | 19 |
| Renal/urinary Gynecological | 0 | 1 | 0 | 0 | 19 |
| 1 | 1 | 0 | 0 | 19 | |
| Respiratory/thoracic/mediastinal | 4 | 0 | 0 | 0 | 19 |
| Skin/subcutaneous | 3 | 3 | 0 | 0 | 19 |
| Vascular disorders (hypertension) | 2 | 3 | 3 | 0 | 19 |
* Gynecological: Pelvic pain: grade 1; Vaginal fistula grade 2