Table 1.
Male |
Female |
|||||||
---|---|---|---|---|---|---|---|---|
WT (n = 7) |
TIL-6 (n = 7) |
p62KI (n = 6) |
p62KI/TIL-6 (n = 3) |
WT (n = 7) |
TIL-6 (n = 10) |
p62KI (n = 7) |
p62KI/TIL-6 (n = 10) |
|
BV/TV (%) | 13.4±2.1 | 13.1±5.9 | 13.5±5.8 | 14.6±4.5 | 13.3±5.6 | 11.9±4.3 | 10.2±2.5 | 11.2±3.9 |
Tb.Th (μm) | 31.4±3.1 | 33.1±5.6 | 36.2±8.5 | 33.1±5.0 | 33.3±4.5 | 35.5±5.3 | 35.5±3.6 | 37.1±9.8 |
Tb.N (1/mm2) | 4.3±0.4 | 3.8±1.1 | 3.7±1.3 | 4.4±0.9 | 4.0±1.6 | 3.5±1.7 | 2.9±0.6 | 3.0±0.1 |
Tb.Sp (μm) | 204.4±22.3 | 248.1±86.0 | 265.4±121.9 | 203.0±48.1 | 239.6±73.0 | 312.0±169.1 | 327.1±84.3 | 313.0±84.2 |
Structural variables for the lumbar vertebral bodies from 12-month-old WT, p62KI, TIL-6, and p62KI/TIL-6 mice. Data are expressed as mean ± SD. No significant differences between WT and other mice in all the variables.
WT = wild-type; BV/TV = cancellous bone volume; Tb.Th = trabecular thickness; Tb.N = trabecular number; Tb.Sp = trabecular separation.