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. Author manuscript; available in PMC: 2015 Mar 16.
Published in final edited form as: Lab Invest. 2014 Mar 31;94(6):633–644. doi: 10.1038/labinvest.2014.51

Figure 6.

Figure 6

Migration of Ang II-treated cardiac fibroblasts (wound-healing assay). Compared with Ang II treatment alone, protease inhibitory AK and CPAI significantly increased cardiac fibroblast migration, whereas vitronectin-binding RR without protease inhibition significantly decreased migration. These results indicate that the migration of cardiac fibroblasts is impacted by both protease inhibition and vitronectin-binding of PAI-1. * vs Cont, # vs Ang + PBS, ‡ vs Ang + RR, P <0.05. N = 3 for each group.