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. Author manuscript; available in PMC: 2015 Jun 6.
Published in final edited form as: Neuroscience. 2014 Mar 26;269:67–78. doi: 10.1016/j.neuroscience.2014.03.014

Table 1.

Body temperature (Tb), blood gas values and integrated phrenic nerve burst amplitude (during acute hypoxia) for i.t treated rats.

Group Tb PaO2 PaCO2 pH MAP Integrated Phrenic amplitude (%)
Baseline AIH + vehicle 37.5 ± 0.2 301.8 ± 9.9 46.6 ± 0.5 7.337 ± 0.015 109.0 ± 3.3 0
AIH + L-NAME 37.8 ± 0.2 288.5 ± 6.4 47.2 ± 1.2 7.326 ± 0.007 111.8 ± 4.8 0
AIH + nNOS-1 37.6 ± 0.1 286.0 ± 7.2 47.2 ± 0.7 7.344 ± 0.009 105.1 ± 2.6 0
AIH + 1400W 37.5 ± 0.2 310.6 ± 13.0 47.3 ± 0.5 7.355 ± 0.001 104.6 ± 6.3 0
Hypoxia AIH + vehicle 37.4 ± 0.2 36.7 ± 1.5* 46.4 ± 0.7 7.330 ± 0.013* 84.5 ± 6.1* 110.8 ± 16.0*
AIH + L-NAME 37.7 ± 0.2 42.0 ± 1.5* 47.6 ± 1.2 7.304 ± 0.010* 72.9 ± 12.8* 62.8 ± 8.4*#
AIH + nNOS-1 37.5 ± 0.1 36.9 ± 1.5* 48.0 ± 0.6 7.322 ± 0.009* 75.2 ± 6.5* 80.6 ± 10.7*#
AIH + 1400W 37.4 ± 0.2 38.7 ± 0.9* 47.3 ± 0.9 7.324 ± 0.007* 79.6 ± 14.8* 106.6 ± 27.5*
60 mins AIH + vehicle 37.4 ± 0.2 280.2 ± 7.0 47.0 ± 0.7 7.336 ± 0.013 90.6 ± 3.9 N/A
AIH + L-NAME 37.8 ± 0.2 268.2 ± 9.0 47.4 ± 1.0 7.319 ± 0.006 96.5 ± 6.6 N/A
AIH + nNOS-1 37.6 ± 0.1 277.5 ± 6.3 47.3 ± 0.7 7.338 ± 0.009 86.0 ± 2.9 N/A
AIH + 1400W 37.5 ± 0.2 292.9 ± 11.9 47.2 ± 0.8 7.351 ± 0.007 87.7 ± 7.8 N/A

Values are means ± 1SEM.

*

significant difference from baseline;

#

significant difference from AIH+vehicle treated group at the respective time point; p<0.05. Tb, body temperature; PaO2 and PaCO2, arterial pressure of oxygen and carbon dioxide, respectively; MAP, mean arterial pressure; amplitude of integrated phrenic nerve burst amplitude expressed as a % change from baseline nerve burst amplitude.