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. Author manuscript; available in PMC: 2015 Mar 16.
Published in final edited form as: Curr Pharm Des. 2012;18(6):748–754. doi: 10.2174/138161212799277833

Figure 1.

Figure 1

To generate the transition list two measures are taken, the first is a measure of the distance between a specific disease and a set of proteins that are known to be associated with a disease, the second is a measure between each protein and the “detectablity” of its constituent peptides. The first measure is based upon NGD and uses literature mining (through annotation associations). The second measure is based upon instrument specific observations and is derived directly from the Atlas.