Table 1.
Association between findings on pathologic examination of LEEP or cone biopsy specimens and presence or absence of residual disease at radical hysterectomy*
| Factor | No residual disease (n = 22) | Residual disease (n = 20) | P value |
|---|---|---|---|
| Histology | 0.74 | ||
| Squamous | 13 (59) | 14 (70) | |
| Adenocarcinoma | 7 (32) | 5 (25) | |
| Adenosquamous | 2 (9) | 1 (5) | |
| Depth of invasion | 0.15 | ||
| > 4.0 mm | 3 (14) | 7 (35) | |
| ≤ 4.0 mm | 19 (86) | 13 (65) | |
| LVSI present | 12 (55) | 5 (25) | 0.07 |
| Positive ECC results | 7 (32) | 11 (55) | 0.66 |
| Positive nodes | 1 (4) | 0 (0) | 1.0 |
| Grade | 0.95 | ||
| 1 | 3 (14) | 3 (15) | |
| 2 | 8 (36) | 10 (50) | |
| 3 | 6 (27) | 6 (30) | |
| LEEP/cone biopsy margin status | <0.001 | ||
| Positive | 8 (36) | 16 (80) | |
| Negative | 10 (45) | 1 (5) | |
| Unknown | 4 (19) | 3 (15) |
LVSI – lymph-vascular space invasion; ECC – endocervical curettage; LEEP – loop electroexcisional procedure.
*
Values in table are numbers (percentages) of patients.