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. Author manuscript; available in PMC: 2016 Mar 2.
Published in final edited form as: Curr Protoc Pharmacol. 2015 Mar 2;68:2.12.1–2.12.26. doi: 10.1002/0471141755.ph0212s68

Fig. 2. Full activation of JNKs requires dual phosphorylation.

Fig. 2

For full activity, JNK family kinases must be phosphorylated at Thr (by MKK7) and Tyr (by MKK4). The cartoon is from (Zhan et al., 2013a).