Table 3.

The association between B12 and incident albuminuria and incident RKF in the Framingham Heart Study

			Model 1			Model 2			Model 3
	n	Events (%)	OR	CI	p-value	OR	CI	p-value	OR	CI	p-value
Albuminuria	1931	214 (11.1)	0.96	0.67-1.38	0.84	0.96	0.66-1.39	0.81	1.17	0.79-1.73	0.44
RKF	2145	237 (11.0)	1.00	0.72-1.53	0.81	0.99	0.69-1.53	0.90	1.32	0.87-2.02	0.19

Model 1: Age- and sex- adjusted.

Model 2: Multivariable-adjusted: Albuminuria - systolic blood pressure, HDL_c, smoking status, hypertension treatment and diabetes.

RKF: diabetes, hypertension, baseline eGFR and dipstick proteinuria.

Model 3: Multivariable-adjusted + baseline lnhomocysteine.

OR are presented per 1SD increase log Vitamin B12.