Table 4.
Molecule | Coupling | F2–F1 (ppm) | Control mean volume/Cr | RBT mean volume/Cr | % Diff between mean and RBT | Effect size |
---|---|---|---|---|---|---|
NAA | -CH3 | 2.00–2.00 | 1.215 ± 0.101 | 1.294 ± 0.070 | 7 ± 10 | 0.95 |
tCho | (CH3)3-N + −CH2-CH2-OH | 3.51-4.05 | 0.018 ± 0.002 | 0.020 ± 0.016 | 11 ± 81 | 0.23 |
(CH3)3-N + −CH2-CH2-OH | 3.20-3.20 | 0.726 ± 0.009 | 0.774 ± 0.052 | 7 ± 7 | 1.63 | |
mI | -CH(OH)-CH(OH) | 3.63–3.29 | 0.029 ± 0.013 | 0.032 ± 0.011 | 10 ± 61 | 0.26 |
3.55–3.55 | 0.342 ± 0.013 | 0.354 ± 0.029 | 4 ± 10 | 0.58 |
Data are presented as described in Table 3, that is, relative to creatine. In all cases, the differences between control and RBT were not statistically significant.
Abbreviations: mI, myo-inositol; NAA, N-acetyl aspartate; RBT, repetitive brain trauma; tCho, total choline. In bold are the proton groups that give rise to the crosspeak chemical shifts indicated in the third column.