. Author manuscript; available in PMC: 2015 Mar 16.

Published in final edited form as: Nutr Metab Cardiovasc Dis. 2009 Oct 9;20(10):698–705. doi: 10.1016/j.numecd.2009.06.011

Table 3.

Odds ratio for obesity depending on ADAM17 genotypes.

Genotype	OR (95% confidence interval)	P^*	P^* for trend
ADAM17_m1254A>G
AA (n=615)	1 (Reference)	0.003	0.003
AG+GG (n=321)	1.56 (1.16–2.08)
ADAM17_i14121C>A
CC (n=677)	1 (Reference)	0.878	0.878
AA+AC (n=259)	0.98 (0.71–1.34)
ADAM17_i33708A>G
AA (n=385)	1 (Reference)	<0.001	0.001
AG (n=441)	0.94 (0.55–1.61)	0.001
GG (n=110)	0.37 (0.28–1.72)
ADAM17_i488274A>C
AA (n=446)	1 (Reference)	0.598	0.426
AC (n=389)	1.16 (0.71–1.89)	0.261
CC (n=101)	0.88 (0.61–1.61)
ADAM17_i53440C>T
CC (n=230)	1 (Reference)	0.018	0.057
CT (n=476)	1.34 (0.95–1.87)	0.237
TT (n=230)	1.64 (0.67–1.51)

P values were adjusted for age, sex, smoking habit, alcohol consumption, diabetes, coronary heart disease, and family relationships.