Fig. 4.

Representative MALDI-TOF mass spectra of the products of the incubation of 450 µM NAMI-A with 20 µM DNA T₆GGT₅ or RNA U₆GGU₅ at pH 6.0 and 7.4, with and without 2.5 mM ascorbate. Reactions were run for 6 h at 37 °C in 100 mM NaNO₃ and 2 mM Mg(NO₃)₂. Filled squares denote the unmodified, full-length T₆GGT₅ and U₆GGU₅ strands and open squares denote singly depurinated oligonucleotides