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. Author manuscript; available in PMC: 2016 Apr 30.
Published in final edited form as: Nitric Oxide. 2014 Nov 25;46:66–71. doi: 10.1016/j.niox.2014.11.012

Figure 1.

Figure 1

Hypothetical model for protective function of H2S in skeletal muscle myopathy/dysfunction induced by metabolic syndromes such as diabetes and obesity. H2S may reverse changes in epigenetic modifications induced by metabolic syndromes. Metabolic syndromes are perceived to cause vascular [73] and mitochondrial [74] dysfunction potentially through Epigenetic modifications. H2S by mitigating vascular dysfunction and by preventing mitochondrial damage might reverse deterioration of muscle function as well as alleviation of other symptoms associated with metabolic syndromes.