Skip to main content
. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Psychopharmacology (Berl). 2014 Oct 11;232(7):1245–1260. doi: 10.1007/s00213-014-3759-z

Figure 6.

Figure 6

Environmental factors altered the Tcor response to MDMA. Animals were placed on a treadmill at 22 or 32 °C. The treadmill motor power was turned on during a time period of 0-30 min (see details in Methods section). Data are mean ± s.e.m (N = 4-8). A, Environmental factors exert a characteristic influence on basal Tcor with the rank order of a multifactorial combination > physical stimulation alone > warm temperature alone. B, The effect of MDMA on Tcor was potentiated by the environmental factors with the rank order of a multifactorial combination > physical stimulation alone > warm temperature alone. *P<0.05, **P<0.01, ***P<0.001 vs. freely behaving rats at 22 °C.