Table 2.

Association of Soluble P-selectin with the ABI and Prevalent PAD^*

	ABI at Exam 3 Beta (95%CI)	p-value	Prevalent PAD Exam 3 OR (95%CI)	p-value
Demographics†	−0.009 (−0.013, −0.006)	<0.001	1.21 (1.06, 1.37)	0.004
+Lifestyle and Comorbidities‡	−0.009 (−0.012, −0.006)	<0.001	1.18 (1.04,1.34)	0.01
+Lipids, glucose, blood pressure§	−0.008 (−0.011, −0.005)	<0.001	1.18 (1.04, 1.35)	0.01
+CRP, IL-6, D-Dimer, Fibrinogen	−0.007 (−0.011, −0.004)	<0.001	1.17 (1.02, 1.33)	0.03

^*P-selectin per standard deviation (SD), which is 13.9 ng/mL; ABI at Exam 3 excluding ABI>1.4; Prevalent PAD defined as ABI≤0.90, excluding ABI>1.4

^†Includes age, race, sex

^‡Adds ever smoker, BMI, hypertension, diabetes, estimated glomerular filtration rate

^§Adds HDL cholesterol, LDL cholesterol, triglycerides, glucose, systolic blood pressure, diastolic blood pressure