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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Cell Signal. 2015 Jan 22;27(5):923–933. doi: 10.1016/j.cellsig.2015.01.009

Figure 1. PAI-1 expression is elevated in smooth muscle cells of the neointimal compartment of injured vessels.

Figure 1

(A) RNA was extracted from balloon catheter-denuded and contralateral control carotid arteries one week following injury. Northern blots were hybridized using 32P-labeled cDNA probes to PAI-1 and A50 (loading control). (B) Paraffin sections (5 μm) of ligated (i–iii) and contralateral control (iv–vi) carotids were stained with H&E (i, iv) or processed for immunohistochemical detection of smooth muscle cell α-actin (ii, v) or PAI-1 (iii, vi) 14 days after common carotid artery ligation. Scale bar=100 μm.