Figure 10. Comparison of rotenone (red, A) with benomyl (blue, B) effects on DOPAL (circles) and DOPAC (squares) levels and DOPAC:DOPAL ratios (C) in test tubes after incubation with ALDH2 and NAD+.
Benomyl potently inhibited conversion of DOPAL to DOPAC, whereas rotenone exerted only a mild effect.