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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Cell Signal. 2015 Feb 12;27(5):908–922. doi: 10.1016/j.cellsig.2015.02.003

Figure 4. UCR1C prevents ISO-induced cardiomyocyte hypertrophy.

Figure 4

UCR1C inhibits ISO-induced cardiomyocyte hypertrophy. NRVMs were transfected with Cerulean-UCR1C or Cerulean control vector then treated with ISO for 48 hours to induce hypertrophy. Cells were fixed, permeabilized, and stained with α-actinin (Red) for cell imaging. Representative images are shown in 4A. Cardiomyocytes with both α-actinin staining and Cerulean expression were selected for cell size measurements. The quantified results are shown in 4B. Data are expressed as mean ± s.e.m. The number of cells counted is indicated. Differences in quantitative variables were examined by one-way analysis of variance (ANOVA). A p-value < 0.001 was considered extremely significant (***) and < 0.05 was significant (*).