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. Author manuscript; available in PMC: 2016 Feb 21.
Published in final edited form as: J Theor Biol. 2014 Dec 12;367:222–229. doi: 10.1016/j.jtbi.2014.12.004

Figure 1.

Figure 1

Schematic of free virus and synaptic transmission modes. (a) In free virus transmission, viruses are released by an infected cell (grey) and can enter the target cell population. Different virus fates are shown with different target cells. Clockwise from the top: a single virus infects the target cell but remains unintegrated, a single virus infects a target cell and is integrated into the genome, multiple viruses infect a target cell but all remain unintegrated, and multiple viruses infect a target cell and some become integrated. (b) Synaptic transmission potentially involves a high number of viruses transferring into a target cell at once. These viruses can be integrated into the genome or remain unintegrated. In contrast to free virus transmission, the multiplicity of infection can be much higher. A single infected cell can potentially transmit via both modes of transmission.