Table 3.
Changes in Mean 48-Hour pH Parameters From Before Treatments to 6-Month Follow-Up in Both Treatment Groups.
| pH Parameters | TIF group (n = 39); Difference in Means (95% CI) | P Valuesa | PPI group (n = 21); Difference in Means (95% CI) | P Valuesa |
|---|---|---|---|---|
| Number of refluxes | −59.9 (−80.7 to −39.2 | <.001 | −99.1 (−133.7 to −64.5) | <.001 |
| Number of long refluxes (>5 minutes) | −4.1 (−6.1 to −2.0) | <.001 | −7.9 (−10.9 to −4.9 | <.001 |
| Duration of longest reflux, minutes | −7.9 (−15.6 to −0.3) | .042 | −2.7 (−13.3 to 7.9) | .598 |
| Fraction time pH < 4, % | −3.4 (−4.9 to −1.9) | <.001 | −5.5 (−7.4 to −3.6) | <.001 |
| DeMeester score | −11.6 (−17.4 to −5.9) | <.001 | −16.5 (−23.0 to −10.0) | <.001 |
Abbreviations: PPI, proton pump inhibitor; TIF, transoral incisionless fundoplication; CI, confidence interval.
a
P values were calculated with paired t test.