Table 4.
Changes in Mean Symptom Scores in Patients With Abnormal Distal Esophageal Acid Exposure From Before Treatments to 6-Month Follow-up in Both Treatment Groups.
| Questionnaires/Symptoms | TIF Group (n = 18); Difference in Means (95% CI) | P Valuesa | PPI Group (n = 10); Difference in Means (95% CI) | P Values |
|---|---|---|---|---|
| GERD-HRQL score | −17.9 (−25.8 to −10.1) | <.001 | −3.6 (−9.6 to 2.4) | .206 |
| Heartburn score | −12.2 (−18.1 to −6.3) | <.001 | −2.6 (−5.7 to 0.5) | .090 |
| Regurgitation score | −2.9 (−3.5 to −2.2) | <.001 | −0.7 (−1.4 to 0) | .042 |
| RDQ score | −2.7 (−3.3 to −2.0) | <.001 | −0.7 (−1.5 to 0.1) | .071 |
| RSI score | −15.3 (−20.3 to −10.3) | <.001 | −1.3 (−6.3 to 3.7) | .574 |
Abbreviations: GERD-HRQL, gastroesophageal reflux disease health-related quality of life; RDQ, Reflux Disease Questionnaire; RSI, Reflux Symptom Index; PPI, proton pump inhibitor; TIF, transoral incisionless fundoplication.
a
P values were calculated using paired t test.