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. 2015 Feb;40(2):124–132. doi: 10.1177/1753193413519926

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© The Author(s) 2014

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm).

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Figure 2. — Change in ROM by joint type and time after CCH injection.*

*Across all five treatment cycles.

^†Legend definitions change for these time points: 1st injection = joints that received only 1 injection; 2nd injection = joints that received 1 or 2 injections; 3rd injection = joints that received 1, 2, or 3 injections.

*Across all five treatment groups.

CI: confidence interval; CCH: collagenase Clostridium histolyticum; CID: clinically important difference; MP: metacarpophalangeal; PIP: proximal interphalangeal; ROM: range of motion.