Table 1.

Age (Years) at First Reported Airway-Related Symptoms (All Registry Patients).

	Hurler	Hurler-Scheie	Scheie	Alla
Macroglossia, No.	137	43	14	203
Median age first reported	1.4	5.0	9.5	1.7
Range	0.2-12.2	0.2-22.7	4.0-38.8	0.2-38.8
Enlarged tonsils, No.	127	49	20	205
Median age first reported	1.7	4.0	5.2	2.5
Range	0.1-14.0	−0.2-15.2	1.5-16.5	−0.2-16.5
Reactive airway disease/asthma, No.	59	19	11	89
Median age first reported	1.8	6.1	5.6	2.8
Range	−0.1-13.0	0.1-14.8	0.2-37.8	−0.1-37.8
Sleep disturbances, No.	184	62	25	278
Median age first reported	1.3	4.0	6.8	1.7
Range	−0.1-12.9	−0.3-28.9	0.0-38.6	−0.3-38.6

^aIncludes patients with unknown phenotype.