Table 1.
General characteristics of healthy subjects and patients with MS.
| HC(n = 112) | All MS(n = 118) | CIS(n = 14) | RRMS(n = 34) | SPMS(n = 35) | PPMS(n = 35) | |
|---|---|---|---|---|---|---|
| Age, years | 41.0 (28.0–52.0) | 45.5 (38.0–54.0) | 38.5 (27.3–42.3) | 39.0 (32.3–47.3) | 48.0 (40.0–55.0) | 54.0 (46.0–56.0) |
| Sex, % female | 78.6 | 71.2 | 71.4 | 82.4 | 71.4 | 60.0 |
| Age of onset of MS, years | 34.5 (26.9–42.2) | 37.3 (25.0–41.9) | 32.0 (26.8–37.5) | 29.0 (24.0–39.0) | 40.0 (34.0–49.0) | |
| Duration of MS, years | 7.5 (2.8–17.0) | 0.6 (0.1–1.3) | 4.0 (1.6–11.5) | 16.0 (10.0–24.0) | 9.0 (5.0–17.0) | |
| EDSS score | 5.0 (2.5–6.5) | 1.0 (0.0–1.5) | 2.3 (1.0–3.5) | 6.5 (5.5–8.0) | 6.5 (5.5–7.0) | |
| MSSS | 6.6 (3.8–8.8) | 2.4 (0.7–4.2) | 4.4 (2.2–6.2) | 7.8 (5.8–9.1) | 8.5 (6.6–9.5) |
All values except for sex presented as medians (interquartile ranges).
HC: healthy control subjects; All MS: total group of MS patients; CIS: clinically isolated syndrome; RRMS: relapsing–remitting MS; SPMS: secondary progressive MS; PPMS: primary progressive MS; EDSS: Expanded Disability Status Scale; MSSS: MS Severity Score.