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. 2015 Mar 16;10(3):e0119709. doi: 10.1371/journal.pone.0119709

Fig 5. FcγRI KO and quad FcγR KO spleen cells are less sensitive to PTX3 induced fibrocyte differentiation.

Fig 5

Spleen cells were cultured for 5 days in the A-D) absence or E-H) presence of PTX3, from A and E) wildtype C57BL/6 mice, B and F) quadruple FcγRI/IIb/III/IV, C and G) FcγRI, and D and H) FcγRIIb knockout mice. After 5 days, cells were air-dried, fixed, and stained, and the number of fibrocytes was counted. Bar is 100 μm. I) For each strain, the count in the presence of PTX3 was normalized to the count in the absence of PTX3. Values are mean ± SEM (n = 3). *p <0.05, **p <0.01 (ANOVA), compared to SFM. ## p<0.01 (ANOVA) compared to C57BL/6.