Table 2. List of initial concentrations and rate constants obtained through curve-fitting optimization on the system of differential equations presented in S2 Fig.

Initial concentration	Values
[GAPDH]	1.35
[GAPDH2]	0
[GAPDH4]	0
[GAPDH-NAD+]	0
[GAPDH2-NAD+2]	0
[GAPDH4-NAD+4]	0
[GAPDH4-telomere2]	0
[NAD+]	0, 50, 75, 100
[telomere]	0.133