EEG recordings from 2 electrodes (EEG1, 2), time-locked to EMG to identify tic-like movements (which were also identified on time-locked video), after intra-DLS PTX (n=4). A. Sample EEG and EMG 5 minutes after 0.2 ug of PTX; emission of tic-like movements, scored from EMG and video, is indicated by arrows. Tic-like movements frequent did not correlate with EEG complexes under these conditions (see 2D). B. Sample EEG from the same mouse 20 minutes after 0.4 ug PTX. Tics after this larger PTX dose were generally associated with pronounced electrographic complexes, as indicated. C. An episode of electrographic seizures 40 minutes after 0.4 ug intrastriatal PTX. D. Time distribution of tics not accompanied by EEG complexes and of the EEG complexes without tics (total number of 10s epochs = 48).