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Latency to first tic and number of tics evoked by 0.1 and 0.2ug of PTX at three sites
| Latency (minutes; median and interquartile range) | 0.1ug | N = | 0.2ug | N = |
|---|---|---|---|---|
| Cx | 8.75 (6.4–12) | 11 | 9 (6.5–11.2) | 11 |
| DLS | 9 (6–11) | 7 | 6 (5–8) * | 9 |
| CES | 9.75 (6.5–13) | 4 | 6.25 (4.7–9) | 8 |
| Number of Tics (mean ± SEM)
| ||||
| Cx | 161.6 (34) | 11 | 226.6 (35) | 11 |
| DLS | 155.7 (46) | 7 | 248.4 (59) | 9 |
| CES | 13.3 (8.4) | 4 | 205.3 (68) | 8 |
Cx - Sensorimotor Cortex; DLS - Dorsolateral Striatum; CES - Central Striatum.
P<0.05 compared with Cx
