Fig 8. Differential unmasking of the surface antigen SmCD59a by treatment with PZQ, ART and OXA.
Drugs were added either at day 7 or day 14 and analyzed 2 days after administration of PZQ and ART and 6 days after OXA application. For the analysis of antigen accessibility, schistosomula were incubated with anti-SmCD59a antiserum. Antibody binding was detected with a fluorophore-labeled anti-rat IgG (IF). Corresponding lower images show the bright field images (BF). Scale bars = 100 μm.