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. 2015 Mar 16;10(3):e0116938. doi: 10.1371/journal.pone.0116938

Fig 5. Caveolin-1 is involved in the regulation of ENaC by EGF and H-Ras.

Fig 5

A. Immuno blot analysis of phosphorylated ERK1/2 (phospho-ERK1/2) and total ERK1/2 in FRT cells transfected with a scrambled siRNA or the siRNA directed against Cav-1 treated with (+) or without (-) EGF. B. Immunoblot analysis of phosphorylated ERK1/2 and total ERK1/2 in FRT cells transfected with wt-Cav-1. C. Iami (normalized) in FRT cells transfected with wild-type α-, β-, and γ-ENaC subunits. Cells were co-transfected with the wtCav-1, scrambled siRNA, siRNA directed against Cav-1, H-RasG12V or H-RasS17N as indicated.