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. Author manuscript; available in PMC: 2015 Mar 17.
Published in final edited form as: J Psychopharmacol. 2012 Oct 31;27(2):192–202. doi: 10.1177/0269881112464828

Figure 5.

Figure 5

Effects of norBNI, (1,10 mg/kg), 5’-AMN (1 mg/kg), and 5’-MABN (1,10 mg/kg) on depression-related behaviour in mice. The time spent immobile (A), swimming (B) and climbing (C) during a 6 min FST is shown. In the TST, a decrease in average force corresponds to increased immobility (D). Depression-related behaviours were measured in the same groups of animals on successive days following a single injection of antagonist, and 30 min after U50,488 (5 mg/kg) or fluoxetine (10 mg/kg) administration. Data are expressed as mean ± SEM, n = 10 per group. Comparisons to saline: *P < 0.05, **P < 0.01, ***P < 0.001.