Table 4.
Plasma concentrations of lipoprotein(a) (Lp(a)) and low-density lipoprotein cholesterol (LDL-C) in patients with isolated Lp(a) elevation before, in first month, and during steady state of chronic lipoprotein apheresis (LA)
| Lp(a) | Before LA | First month | Steady state | Mean total Lp(a) reduction (%) |
| Cmax before LA (mg/dL) | Not done | 97.2 ± 56.0 | 74.5 ± 24.3 | |
| Cmin after LA (mg/dL) | Not done | 39.6 ± 23.1 | 24.5 ± 8.9 | |
| Reduction by LA (%) | Not done | 59.5 ± 11.9 |
66.8 ± 5.8 (p < 0.0001) |
|
| Interval mean level (mg/dL) | 127.2 ± 67.3 | 81.2 ± 45.8 | 60.0 ± 19.5 |
52.8 ± 23.0 (p < 0.0001) |
| LDL-C | Before LA | First month | Steady state | Mean total LDL-C reduction (%) |
| Cmax before LA (mg/dL) | Not done | 92.6 ± 33.9 | 91.7 ± 27.9 | |
| Cmin after LA (mg/dL) | Not done | 41.0 ± 18.2 | 31.8 ± 15.6 | |
| Reduction by LA (%) | Not done | 55.3 ± 12.9 |
65.7 ± 8.7 (p < 0.0001) |
|
| Interval mean level (mg/dL) | 96.1 ± 33.5 | 77.7 ± 28.1 | 74.3 ± 23.7 |
22.7 ± 31.2 (p < 0.0001) |