Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Efficacy of NP HDACIs as radiosensitizers in chemoradiotherapy for solid tumor cell lines in vivo. Mice bearing flank tumor xenografts were administered (intravenous) with saline, vorinostat, NP vorinostat, quisinostat or NP quisinostat followed by radiotherapy. Tumors were irradiated to a total dose of 3 Gy at 3 h after chemotherapy injection. Changes in tumor volume were measured and the tumor growth delay curves for mice bearing PC3 (A) and SW620 (B) tumors were generated.
