Table 1. The known functional sites (FSs) and predicted results on the tRNA(Lys,3)(PDB#1FIR).
| Site No | FS | Predicted FS | Description |
|---|---|---|---|
| 1 | 1–4 | 1,2 | Within acceptor stem(5' end)Interacting with RanContacting XpotInvolved in recognition by RNase Z and RNase PRecognized by aminoacyl-tRNA synthetase |
| 2 | 13–22 | 13,17,19,20,22 | DHU loopInteracting with the mRNA-ribosome complexContacting XpotInvolved in recognition by RNase P |
| 3 | 34–36 | 35 | Anticodon, Decoding mRNA codonRecognized by aminoacyl-tRNA synthetaseInteracting with the mRNA-ribosome complex |
| 4 | 49–51 | 49 | Within TψC stemBinding site of elongation factor |
| 5 | 53–61 | 56,60 | TψC loopInteracting with the mRNA-ribosome complexContacting XpotInvolved in recognition by RNase Z and RNase PProcessed by a tRNA ψ55 pseudouridine synthaseAffect 3' end processing and tRNA structure |
| 6 | 63–65 | 64 | Within TψC stemBinding site of elongation factorInteracting with RanInvolved in recognition by RNase P |
| 7 | 72–76 | 76 | Aminoacylation site(3' end)Recognized by aminoacyl-tRNA synthetaseInteracting with the mRNA-ribosome complex (7)Contacting Xpot (1)Involved in recognition by RNase ZProcessed by a CCA-adding enzyme |