Table 3.
Average composite z-score results from GEE models
| Magnitude of difference (SE) | p-value | ||
|---|---|---|---|
| Model 1 (n = 270) | Univariate | −0.16 (0.090) | 0.08 |
| Model 2 (n = 266) | + MCS, PCS, PSS-4, CES-D-4 | 0.034 (0.11) | 0.75 |
| Model 3 (n = 266) | + Income | −0.043 (0.11) | 0.69 |
| Model 4 (n = 254) | + Hypertension, dyslipidemia, heart disease | −0.051 (0.12) | 0.67 |
| Model 5 (n = 229) | + eGFR | −0.14 (0.19) | 0.46 |
| Model 6 (n = 229) | + Stroke | −0.14 (0.18) | 0.45 |
GEE stands for generalized estimating equation. SE stands for standard error. A negative magnitude of difference indicates that participants with Fabry disease have a lower z-score than REGARDS control participants
MCS stands for mental component score. PCS stands for physical component score. PSS-4 stands for the 4-item Perceived Stress Scale. CES-D-4 stands for the 4-item the Center for Epidemiologic Studies Depression Scale. eGFR stands for estimated glomerular filtration rate