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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Pharmacogenomics. 2014 Nov;15(14):1823–1838. doi: 10.2217/pgs.14.134

Table 5.

SULT1A1 genetic variation and chemopreventives (flavonoids, isoflavonoids and other phenols).

Study (year) Chemopreventive agent Population Cases/controls (n) Main findings Ref.
Nagar et al. (2006) Chrysin, genistein, quercetin Recombinant proteins None Vmax*1 > *3 > *2 [12]
Ung et al. (2007) Apigenin, epicatechin, resveratrol Recombinant proteins None Vmax*1 > *3 > *2 [85]
Kellen et al. (2006) Fruit (antioxidants) Belgian 200/385 NA between SULT1A1*1/2 SNP and ever-smokers in bladder cancer risk Decreased risk with high daily fruit consumption [69]
Rybicki et al. (2011) Red wine (resveratrol) African–American and Caucasian American 391 prostate cancer cases 33% PhIP-DNA adducts explained by SULT1A1 and UGT1A10 SNPs, and African ancestry [86]

NA: No association; PhIP: 2-amino-1-methyl-6-phenylimidazo[4,5-f].