Table 1.
Effect of temperature onto yield and stereoselectivity of the electrochemical reduction of 7a on a lead cathode.
Entrya | T [°C] | yieldb [%] | c.e.c [%] | drd [8a:8b] |
1 | 60 | 33 | 13 | 6.2 |
2 | 40 | 85 | 34 | 5.4 |
3 | 20 | 93 | 38 | 5.2 |
aCatholyte: 0.5% MTES and 2% H2SO4 in MeOH, current density: 12.5 mA cm–2, passed charge: 10 F mol–1, anode: platinum; byield determined by GC (internal standard); cc.e. = current efficiency; dratio determined by NMR spectroscopy.