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. 2015 Mar 17;9:26. doi: 10.3389/fnsys.2015.00026

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Copyright © 2015 Charvet, Kasschau, Datta, Knotkova, Stevens, Alonzo, Loo, Krull and Bikson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Example of hardware-based waveform control. Users are provided with an individual device and accessories such as the 5x-Session Home Kit (A)The subject checks in with the supervisor before and after each session (B). The supervisor unlocks operation before each session by providing a code (B). The subject enters only the code provided with no access to device programming or stimulation settings. The subject uses custom fit headgear to position electrodes (C,D). The device automatically collects compliance data and may also prompt the user for information (E). Details of implementation will be customized to each clinical trial while maintaining the principles of supervised neuromodulation (F, G). (Image courtesy of Soterix Medical Inc.)