Figure 3. Ag presentation by DC subsets in vivo after rAd vaccination.

Frequency of (A) CD8 T cells or (B) CD4 T cells from the spleen that produce IFN, IL-2, or TNF in response to AL11 peptide or Gag protein restimulation at 23 days after vaccination in WT or Batf3^–/– mice. Mice received rAd expressing Gag at 1 × 10⁸ PU for rAd5, chAd3, or chAd63 and 1 × 10⁹ PU for rAd35. Error bars represent mean ± SEM. *P ≤ 0.05, Mann-Whitney test. Data represents 2 independent experiments (n = 4–5).