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. 2015 Mar 12;3:e830. doi: 10.7717/peerj.830

Table 2. Putative biological functions of the differentially expressed genes after listening to music.

Biological function Gene Direction of regulation
Dopamine secretion, transport, signaling SNCA, RTN4, RGS2, SLC6A8 Up
Synaptic neurotransmission (Vesicular exocytosis, endocytosis) SNCA, STXBP2, FKBP8, SYNJ1, LYST, SUMO2, HDAC4, DUSP6 Up
Synaptic function SNCA, NPTN, FKBP8, NRGN, HDAC4 Up
Learning and memory, cognitive performance SNCA, NRGN, NPTN, FKBP8, RTN4, SLC6A8, NEDD9 Up
Song learning and singing in songbirds SNCA, NRGN, RGS2, MYC, UBE2B Up
Auditory cortical activation HDAC4, LRRFIP1 Up
Absolute pitch FAM49B, HDAC4 Up
Neuroprotection SNCA, RTN4, FKBP8, SLC6A8, KLF4 Up
Neurogenesis KLF4, SMNDC1, S100A12 Up
Neuronal apoptosis CASP8, GZMH, GZMA, IFI6, PYCARD, TNFRSF10B, HSPE1 Down
ATP synthase coupled proton transport ATP5J, ATP5L Down