Table 1.

Brain region and peak significance of gray matter (GM) and white matter (WM) volume reduction by group comparison using VBM-DARTEL.

Region	Extent (k)	t-value	MNI coordinates (mm)
			x	y	z
GM: CONTROL vs. PoTS
Left insula (BA13)	59	3.7	−47	−6	11
Right middle frontal gyrus (BA6)	23	3.7	26	14	62
Right cingulate gyrus (BA32)	5	3.6	5	8	47
Right cingulate gyrus (BA24)	3	3.6	11	−3	53
GM: PoTS vs. CONTROL
Right putamen	1	3.5	30	−7	4
Left putamen	4	3.5	−29	−9	6
Right middle temporal gyrus (BA37)	1	3.4	42	−63	−6
WM: CONTROL vs. PoTS
Left precentral gyrus	96	6.8	−18	−18	64
Left paracentral lobule	56	4.9	−12	−34	56
Right postcentral gyrus	16	4.0	44	−28	56
Right superior frontal gyrus	5	4.0	8	16	58
Right paracentral lobule	10	3.7	12	−32	56
Right precentral gyrus	5	3.6	30	−18	68
WM: PoTS vs. CONTROL
Left middle temporal gyrus	10	3.8	−52	−50	0

Table depicts regions with voxel-level significance (uncorrected p < 0.001), the number of voxels in each significant cluster, t-value, and MNI coordinates. GM, gray matter; WM, white matter. Extend threshold was set as 0 voxel for GM contrasts and as 5 voxels for WM contrasts.