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. 2014 Mar 26;1:14004. doi: 10.1038/mtm.2014.4

Figure 2.

Figure 2

SNC-Fc and EC4 reduced apoptosis in macrophages and endothelial cells. Graphs show the percentage of apoptotic (a) macrophages and (b) endothelial cells as assessed by cleaved caspase-3 immunocytochemistry 24 hours after induction of apoptosis with Fas-L and treatment with the purified proteins (mean ± SEM, n = 3, *P < 0.05 versus Fc, fibroblast growth factor receptor (FGFR) mutated and EC4 mutant). EC, extracellular; HUVECs, human umbilical vein endothelial cells; SNC, soluble N-cadherin.