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. 2014 Mar 26;1:14004. doi: 10.1038/mtm.2014.4

Figure 5.

Figure 5

EC4-Fc increases the ratio of smooth muscle cells to macrophages (a marker of plaque stability). (a) Analysis of the ratio of vascular smooth muscle cells (VSMCs; actin) to macrophages (Griffonia simplicifolia lectin-1 (GSL); mean ± SEM, Fc n = 11, SNC-Fc n = 10, EC4-Fc n = 10, *P < 0.05 versus Fc). (b) Representative images of GSL immunohistochemistry for macrophages and actin immunohistochemistry for VSMCs. Higher power images of the actin immunohistochemistry are shown in lower panels for clarity. Bar = 250 µm. EC, extracellular; SNC, soluble N-cadherin.