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. 2014 Jun 11;1:14018. doi: 10.1038/mtm.2014.18

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Copyright © 2014 The American Society of Gene & Cell Therapy

This work is licensed. under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Antibody responses. Immunoglobulin G (IgG) against (a) AAV. (b) GAA. The data were presented as geometric mean (n = 5). The positive error bar represents the upper limit of 95% confidence interval, and the negative error bar the lower limit of 95% confidence interval. Group number indicated on the horizontal axes. Group: 1, vehicle; 2, vector; 3, vehicle; 4, vector; 5, vector, ERT ×2; 6, ERT ×2; 7, vector, ERT ×8; 8, ERT, vector, ERT ×5. ERT, enzyme replacement treatment.