Skip to main content
. 2012 Aug;12(3):158–163. doi: 10.17305/bjbms.2012.2463

FIGURE 1.

FIGURE 1

HIF-1 regulates hypoxia induced Kv channels (Kv1.2 Kv1.5, Kv2.1, and Kv9.3) mRNA expression in PASMCs. PCR amplified products are displayed in agarose gel for Kv1.2 (295 bp, A), Kv1.5 (340bp, B), Kv2.1 (451bp, C), Kv9.3 (568 bp, D) and β-actin (139 bp- A, B, C, and D). N, exposure to normoxia for 18 h; H, exposure to hypoxia for 18 h; W, exposed to hypoxia for 18 h after transfection with wildtype EPO-enhancer fragments; M, exposed to hypoxia for 18 h after transfection with mutant-type EPO-enhancer fragments. Right Panels, Data were normalized to the amount of β-actin. Values are presented as mean±SEM (experiments were independently repeated 5-6 times). *p<0.05 compared with N group; #p<0.05 compared to the hypoxia group.